New Nutrition Guidelines Focus on Gut Health and Long-Term Success
GLP-1 weight loss medications like Wegovy®, Ozempic®, and Mounjaro® are revolutionising obesity care. But they are not a one-size-fits-all solution.
A new 2025 clinical guideline from leading medical organisations offers the first comprehensive nutritional guidance to support people using GLP-1s with emphasis on managing side effects, protecting gut health, and improving long-term adherence.
It stresses the importance of a more holistic approach to care: “During GLP-1 use, nutritional and medical management of gastrointestinal side effects is critical, as is navigating altered dietary preferences and intakes, preventing nutrient deficiencies, preserving muscle and bone mass through resistance training and appropriate diet, and complementary lifestyle interventions.” [1]
Key Nutritional Recommendations for People Using GLP-1s
The expert advisory recommends nutrition strategies that maximise the benefits of GLP-1 therapy and help users feel better, especially when appetite and food volume change.
Key dietary adjustments:
- Small, frequent meals: Prevent nausea and energy dips by avoiding long gaps without eating.
- High-protein intake: Aim for 1.2–1.6 g/kg/day to preserve lean muscle.
- Hydration: Drink water regularly to reduce constipation and support digestion.
- Fiber-rich foods: Gradually increase sources like whole grains, vegetables, or dried fruits. Start slowly if prone to bloating or discomfort.
- Minimally processed foods: Focus on whole ingredients—vegetables, fruits, nuts, seeds, lean protein, and low-fat dairy.
Gut Microbiome Considerations:
The advisory notes that microbiome-targeted strategies, like increasing the consumption of resistant starch, fermentable fibres, or possibly using probiotics, may enhance GLP-1 therapy outcomes. Research is ongoing.
Why Digestive Side Effects Are a Real Barrier
GLP-1s are known for their benefits, but also for their side effects. Common issues include:
- Nausea or reflux.
- Constipation.
- Bloating and gas.
- Cramping and gut discomfort. [2]
These symptoms are the number 1 reason people stop treatment early, which can prevent long-term health benefits like improved cardiovascular and metabolic health. The advisory confirms: nutrition alone may not be enough. Many users need additional support to maintain adherence.
Where Forte80™ Comes In
This is exactly why we developed Forte80™. To help people on GLP-1s stay comfortable, consistent, and confident in their journey.
The daily dose of 2 capsule contains:
- 80 billion CFUs.
- Four carefully selected probiotic strains.
- Clinically relevant dosages formulated for gut health during weight loss.
Forte80™ Helps You:
- Reduce digestive side effects
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- Supports bowel regularity, eases bloating, and improves gut comfort
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Protect your microbiome during dietary change
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Helps maintain microbial balance when food volume and variety decrease
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Stay on track with GLP-1 therapy
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More comfort means fewer interruptions — and ultimately, better outcomes.
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Forte80™ is not a replacement for your medication, but it is a smart partner that helps you feel better while your body adapts.
Final Thought: Better Nutrition, Better Gut Health, Better Results
GLP-1s work best when they are part of a full support system, this includes the right food, hydration, mindset, and gut care. It is about health, so family, friends, health care professional, support groups (in real life or virtual) helps a lot.
The new guidelines show we are entering a new era of patient-centered, gut-conscious obesity care.
Forte80™ is here to help you stay strong, balanced, and well-supported, for your health and happiness.
References:
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Mozaffarian D., et al. Nutritional priorities to support GLP‐1 therapy for obesity: a clinical advisory from the American College of Lifestyle Medicine, the American Society for Nutrition, the Obesity Medicine Association, and The Obesity Society. American Journal of Clinical Nutrition. 2025.
https://pubmed.ncbi.nlm.nih.gov/40445127/
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MHRA. GLP-1 receptor agonists: reminder of the potential side effects and to be aware of the potential for misuse. GOV.UK. 2024.
https://www.gov.uk/drug-safety-update/glp-1-receptor-agonists-reminder-of-the-potential-side-effects-and-to-be-aware-of-the-potential-for-misuse
